Memento is a gem. Leonard lives his life in an endless loop of grief, disorientation, and desire for vengeance. At one point, he asks: "How am I supposed to heal if I can't feel time?"

His wife's death is always fresh in his mind, and he can't remember to forget it.

The scary thing is, anterograde amnesia is a real condition. I think I might prefer to die than to suffer such a permanent hell. Without the ability to consciously learn new things and gain experience, what is life? There's still momentary sensory pleasure, but without retrospection, is there meaning?